UMPS antibody

Catalog No. ABIN7256752

This Rabbit Polyclonal antibody specifically detects UMPS in IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for UMPS antibody (ABIN7256752)

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UMPS antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-UMPS Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human UMPS (NP_000364.1).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UMPS

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Alternative Name: UMPS

Background: This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

Gene ID: 7372

UniProt: P11172

Pathways: Ribonucleoside Biosynthetic Process