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PLOD2 antibody

PLOD2 Reactivity: Human IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7257599
  • Target See all PLOD2 Antibodies
    PLOD2 (Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2))
    Reactivity
    • 22
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 17
    • 6
    Rabbit
    Clonality
    • 19
    • 4
    Polyclonal
    Conjugate
    • 19
    • 2
    • 1
    • 1
    This PLOD2 antibody is un-conjugated
    Application
    • 19
    • 7
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human PLOD2 (NP_891988.1).
    Isotype
    IgG
    Top Product
    Discover our top product PLOD2 Primary Antibody
  • Application Notes
    IF 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PLOD2 (Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2))
    Alternative Name
    PLOD2 (PLOD2 Products)
    Synonyms
    D530025C14Rik antibody, LH2 antibody, Plod-2 antibody, TLH antibody, procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 antibody, procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 antibody, Plod2 antibody, PLOD2 antibody
    Background
    The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Gene ID
    5352
    UniProt
    O00469
    Pathways
    SARS-CoV-2 Protein Interactome
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