SNW1 antibody

Catalog No. ABIN7257970

This anti-SNW1 antibody is a Rabbit Polyclonal antibody detecting SNW1 in WB, IHC and IF. Suitable for Human, Mouse and Rat.

Quick Overview for SNW1 antibody (ABIN7257970)

Target: SNW1 (SNW Domain Containing 1 (SNW1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNW1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SNW1 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human SNW1 (NP_036377.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SNW1

Target: SNW1 (SNW Domain Containing 1 (SNW1))

Alternative Name: SNW1

Background: This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 70 kDa/75 kDa

Calculated_MW: 61 kDa

Gene ID: 22938

UniProt: Q13573

Pathways: Retinoic Acid Receptor Signaling Pathway