OB Cadherin antibody

Catalog No. ABIN7258074

The Rabbit Polyclonal anti-OB Cadherin antibody is suitable to detect OB Cadherin in samples from Human and Rat. It has been validated for IHC.

Quick Overview for OB Cadherin antibody (ABIN7258074)

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OB Cadherin antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-OB Cadherin Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human CDH11 (NP_001788.2).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for OB Cadherin

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Alternative Name: CDH11

Background: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

Gene ID: 1009

UniProt: P55287