CLCNKA antibody

Catalog No. ABIN7260857

The Rabbit Polyclonal anti-CLCNKA antibody has been validated for WB. It is suitable to detect CLCNKA in samples from Human and Mouse.

Quick Overview for CLCNKA antibody (ABIN7260857)

Target: CLCNKA (Chloride Channel Ka (CLCNKA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCNKA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CLCNKA Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human CLCNKA (NP_001244068.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CLCNKA

Target: CLCNKA (Chloride Channel Ka (CLCNKA))

Alternative Name: CLCNKA

Background: This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 75 kDa

Calculated_MW: 70 kDa/75 kDa

Gene ID: 1187

UniProt: P51800

Pathways: Response to Water Deprivation