Glutaredoxin 1 antibody

Catalog No. ABIN7261263

The Rabbit Polyclonal anti-Glutaredoxin 1 antibody has been validated for IHC and IF. It is suitable to detect Glutaredoxin 1 in samples from Human, Mouse and Rat.

Quick Overview for Glutaredoxin 1 antibody (ABIN7261263)

Target: Glutaredoxin 1 (GRX1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutaredoxin 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Glutaredoxin 1 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human GLRX (NP_001112362.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Glutaredoxin 1

Target: Glutaredoxin 1 (GRX1)

Alternative Name: GLRX

Background: This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Gene ID: 2745

UniProt: P35754

Pathways: Cell RedoxHomeostasis