SLC40A1 antibody

Catalog No. ABIN701095

This Rabbit Polyclonal antibody specifically detects SLC40A1 in WB, IHC (p) and IF (p). It exhibits reactivity toward Human, Mouse, Rat, Dog and Pig.

Quick Overview for SLC40A1 antibody (ABIN701095)

Target: SLC40A1 (Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1))

Reactivity: Human, Mouse, Rat, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC40A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SLC40A1 Antibody

Cross-Reactivity: Dog, Human, Mouse, Pig, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLC40A1

Isotype: IgG

Application Details

Application Notes: WB(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SLC40A1

Target: SLC40A1 (Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1))

Alternative Name: SLC40A1

Background:

Synonyms: Ferroportin 1, Ferroportin-1, FPN1, HFE4, IREG1, Iron regulated transporter 1, Iron-regulated transporter 1, MTP1, S40A1_HUMAN, SLC40A1, Solute carrier family 40 member 1, MST079, MSTP079, MTP1, SLC11A3.

Background: SLC40A1 may be involved in iron export from duodenal epithelial cells and also in transfer of iron between maternal and fetal circulation. It mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Defects in SLC40A1 are the cause of hemochromatosis type 4, an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin.

Molecular Weight: 63kDa

Gene ID: 30061

Pathways: Transition Metal Ion Homeostasis