MAP2K4 antibody
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- Target See all MAP2K4 Antibodies
- MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAP2K4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- A synthetic peptide of human MAP2K4
- Isotype
- IgG
- Top Product
- Discover our top product MAP2K4 Primary Antibody
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- Application Notes
- WB 1:1000-1:4000 IHC 1:50-1:200 IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
- Alternative Name
- MAP2K4 (MAP2K4 Products)
- Background
- This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.
- Molecular Weight
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Observed_MW: 44 kDa
Calculated_MW: 44 kDa/45 kDa
- Gene ID
- 6416
- UniProt
- P45985
- Pathways
- MAPK Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
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