PRKAB1 antibody
Quick Overview for PRKAB1 antibody (ABIN7263965)
Target
See all PRKAB1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- A synthetic peptide of human PRKAB1
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Isotype
- IgG
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anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) antibody
PRKAB1 Reactivity: Human WB, IHC, IF Host: Rabbit Monoclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 201-270) antibodyPRKAB1 Reactivity: Mouse, Rat ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (pSer182) antibodyPRKAB1 Reactivity: Human, Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (pSer181) antibodyPRKAB1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) antibodyPRKAB1 Reactivity: Human, Mouse WB, IHC, ICC, IP Host: Mouse Monoclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 1-270) antibodyPRKAB1 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 2C3 unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 13-242) antibodyPRKAB1 Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 1-80) antibodyPRKAB1 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 4-34), (N-Term) antibodyPRKAB1 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB3228 unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 1-270) antibodyPRKAB1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3H12-1A10 unconjugated
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Application Notes
- IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
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Alternative Name
- PRKAB1
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Background
- The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.
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Gene ID
- 5564
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UniProt
- Q9Y478
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Pathways
- AMPK Signaling, Warburg Effect
Target
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