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Histone 3 antibody (pThr11)

This Rabbit Polyclonal antibody specifically detects Histone 3 in IF and IHC. It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN7265086

Quick Overview for Histone 3 antibody (pThr11) (ABIN7265086)

Target

See all Histone 3 (H3) Antibodies
Histone 3 (H3) (Histone H3 (H3))

Reactivity

  • 1344
  • 908
  • 810
  • 41
  • 39
  • 39
  • 34
  • 33
  • 26
  • 23
  • 21
  • 21
  • 6
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  • 4
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  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Mouse, Rat

Host

  • 1156
  • 251
  • 8
  • 5
Rabbit

Clonality

  • 1074
  • 345
  • 1
Polyclonal

Conjugate

  • 814
  • 72
  • 44
  • 44
  • 44
  • 44
  • 44
  • 44
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  • 1
This Histone 3 antibody is un-conjugated

Application

  • 1029
  • 417
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  • 322
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  • 7
  • 7
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  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
Immunofluorescence (IF), Immunohistochemistry (IHC)
  • Binding Specificity

    • 52
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    • 44
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    pThr11

    Characteristics

    Phosphorylated antibody

    Purification

    Affinity purification

    Immunogen

    A phospho specific peptide corresponding to residues surrounding T11 of human HIST1H3B

    Isotype

    IgG
  • Application Notes

    IHC 1:50-1:200 IF 1:50-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    Histone 3 (H3) (Histone H3 (H3))

    Alternative Name

    Histone H3

    Background

    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

    Gene ID

    8350

    UniProt

    P68431
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