TRAFs and NIK-Associated Protein (TNAP) antibody

Catalog No. ABIN7013886

This Mouse Monoclonal antibody specifically detects in FACS and ICC. It exhibits reactivity toward Human, Dog, Goat, Monkey, Pig and Sheep.

Quick Overview for TRAFs and NIK-Associated Protein (TNAP) antibody (ABIN7013886)

Target: TRAFs and NIK-Associated Protein (TNAP)

Reactivity: Human, Dog, Goat, Monkey, Pig, Sheep

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: W8B2B10

Product Details

Purpose: Anti-TNAP

Specificity: The mouse monoclonal antibody W8B2B10 recognizes TNAP (tissue non-specific alkaline phosphatase), an ectoenzyme expressed mainly on embryonic stem cells, liver, bone, and kidney cells. This antibody is suitable for characterization of bone marrow-derived MSCs, iPSCs, and ESCs.

Purification: Purified by protein-A affinity chromatography.

Immunogen: WERI-RB-1 retinoblastoma cell line

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details

Target: TRAFs and NIK-Associated Protein (TNAP)

Alternative Name: TNAP

Background: Alkaline phosphatase, biomineralization associated,Tissue non-specific alkaline phosphatase (TNAP), also known as liver/bone/kidney alkaline phosphatase, or MSCA-1 (mesenchymal stem cell antigen 1) is a selective marker for the prospective isolation of bone marrow-derived mesenchymal stem cells and mesenchymal stem-like cells. It is expressed at high levels in liver, bone, kidney, or endometrium, as well as on embryonic stem cells (ESCs). TNAP also plays a role in bone mineralization. Mutations in TNAP gene are associated with hypercalcemia and skeletal defects (hypophosphatasia).,Tissue Non-specific Alkaline Phosphatase, MSCA-1, liver/bone/kidney alkaline phosphatase

Gene ID: 249

UniProt: P05186