F11R antibody (AA 51-150)

Catalog No. ABIN702130

This Rabbit Polyclonal antibody specifically detects F11R in WB and ELISA. It exhibits reactivity toward Rat.

Quick Overview for F11R antibody (AA 51-150) (ABIN702130)

Target: F11R (F11 Receptor (F11R))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F11R antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-F11R Antibody

Binding Specificity: AA 51-150

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Junctional Adhesion Molecule 1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for F11R

Target: F11R (F11 Receptor (F11R))

Alternative Name: JAM1

Background:

Synonyms: JAM, KAT, JAM1, JAMA, JCAM, CD321, PAM-1, Junctional adhesion molecule A, JAM-A, Junctional adhesion molecule 1, JAM-1, Platelet F11 receptor, Platelet adhesion molecule 1, F11R, UNQ264/PRO301

Background: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

Gene ID: 50848

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization