Recombinant Muscle Acetylcholine Receptor antibody
Reactivity: Human, Mouse, Rat
BP, ELISA, WB
Host: Rat
Monoclonal
mAb 192
unconjugated
Recombinant Antibody
-
- Target
- Muscle Acetylcholine Receptor
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human, Mouse, Rat
- Host
- Rat
- Clonality
- Monoclonal
- Application
- Blocking Peptide (BP), ELISA, Western Blotting (WB)
- Purpose
- Anti-Human Muscle Acetylcholine Receptor [mAb 192], Rat IgG2b, kappa
- Specificity
- The antibody binds to human muscle AChR with a Kd of 10 pM, to mouse muscle AChR with a Kd of 50 pM, and to rat muscle AChR with a Kd of 646 nM.
- Cross-Reactivity
- Mouse, Rat
- Characteristics
-
Original Species of Ab: Rat
Original Format of Ab: IgG2b
- Purification
- Protein A affinity purified
- Immunogen
- Human muscle AChR.
- Clone
- MAb 192
- Isotype
- IgG2b kappa
-
- Application Notes
- This antibody binds to the human muscle Acetylcholine receptor, which is a ligand-gated ion channel, transducing an action potential into the muscle cells. The antibody binds to the main immunogenic region (MIR) and prevents ligand-binding.
- Restrictions
- For Research Use only
-
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % Proclin 300.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
- Target
- Muscle Acetylcholine Receptor
- Background
- AChR
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