Recombinant CD81 antibody

Catalog No. ABIN7072376

The Mouse Monoclonal anti-CD81 antibody has been validated for FACS, WB, ELISA, IP, IF, Func, IHC (p) and ICC. It is suitable to detect CD81 in samples from Human, Sheep, Goat and Chimpanzee.

Quick Overview for Recombinant CD81 antibody (ABIN7072376)

Target: CD81

Antibody Type: Recombinant Antibody

Reactivity: Human, Sheep, Goat, Chimpanzee

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD81 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Clone: 1D6

Product Details anti-CD81 Antibody

Purpose: Anti-CD81 [1D6], Mouse IgG1, kappa

Specificity: This antibody is specific for human CD81, which is expressed on most tissues with the exception of red blood cells and platelets.

Cross-Reactivity: Chimpanzee, Goat, Sheep

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: This antibody was produced by immunizing mice with 5A6-aggregated OCI-LY8 B cells.

Isotype: IgG1 kappa

Application Details

Application Notes: This antibody is a strong inducer of homotypic adhesion in hematolymphoid cells (Levy, 1998). This antibody also has an anti-proliferative effect, and is able to induce growth inhibition of B cell lines. Triggering of CD81 by this antibody induces a significant upregulation of the constituitive release of TNF-α by JY cells, an Eptsein-Barr virus-positive B lymphoblastoid cell line (Altomonte, 1995).

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for CD81

Target: CD81

Alternative Name: CD81

Background: Tetraspanin-28, TAPA-1, Target of the Antiproliferative Antibody 1, Tspan-28

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C