Recombinant Lewis Blood Group A/b antibody
Quick Overview for Recombinant Lewis Blood Group A/b antibody (ABIN7072596)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Lewis a,b [HEA164], Rabbit IgG, kappa
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Specificity
- This antibody is specific for Lewis a,b carbohydrate antigens.
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Characteristics
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Original Species of Ab: Mouse
Original Format of Ab: IgM
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Purification
- Protein A affinity purified
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Immunogen
- This antibody was raised by immunising mice with human carcinoma cells.
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Isotype
- IgG kappa
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Application Notes
- This antibody has applications in the detection of normal and neoplastic epithelial cells. This antibody has been shown to react with a glycolipid fraction isolated from colon carcinoma tissue, with no effect of pronase E addition on its reactivity (Moldenhauer et al, 1987). This antibody, when immobilised on the wall of a shear chamber, has been shown to support slow leukocyte rolling (Chen et al, 1997).
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Comment
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgM format, for improved compatibility with existing reagents, assays and techniques.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Lewis Blood Group A/b
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Alternative Name
- Lewis a,b
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Background
- Blood Group Lewis a/b, lewis a, lewis b
Target
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