Recombinant CD31 antibody

Catalog No. ABIN7072617

This anti-CD31 antibody is a Rabbit Chimeric antibody detecting CD31 in IHC. Suitable for Human.

Quick Overview for Recombinant CD31 antibody (ABIN7072617)

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This CD31 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: BAG-85D10

Product Details anti-CD31 Antibody

Purpose: Anti-CD31 [BAG-85D10], Rabbit IgG, kappa

Specificity: This antibody recognises CD31 (PECAM1) which is a member of the immunoglobulin superfamily and is expressed at various circulatng cells, such as neutrophils, monocytes, platelets as well as on endothelial cells. CD31 is a cell adhesion molecule and is involved in the leukocyte transendothelial migration during inflammation.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: This antibody was raised by immunising mice with human peripheral blood lymphocytes from a patient with high numbers of gamma-delta T cells.

Isotype: IgG kappa

Application Details

Application Notes: This antibody is recommended for the detection and identification of megakaryocytes and thrombocytes. It was used to analyse megakaryocytes in the fetal hepatoblastoma tissue samples (von Schweinitz et al., 1995).

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for CD31

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Alternative Name: CD31

Background: PECAM1, Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', PECA1, JC/70A, BAG 85D10

UniProt: P16284

Pathways: Regulation of Actin Filament Polymerization