ABCA7
Reactivity: Human
FACS, IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 680
Application Notes
IHC/IF (M,R) 1:1500-1:3000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Target
ABCA7
(ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))
Alternative Name
ABCA7
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known, however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system.