OB Cadherin antibody

Catalog No. ABIN7073255

Product Details anti-OB Cadherin Antibody

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OB Cadherin antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse OB Cadherin

Application Details

Application Notes: WB (H,M,R) 1: 500-1: 1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for OB Cadherin

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Alternative Name: OB Cadherin (CDH11 Products)

Background: The cadherin super family comprises a large number of membrane glycoproteins with one or more cadherin repeats, which are involved in Ca2+ dependent cell-cell adhesion. Cadherin-11, also known as OB-cadherin, is a type II classical cadherin. Classical cadherins are type I transmembrane proteins with an N-terminal extracellular domain containing five tandem cadherin repeats and a C-terminal cytoplasmic domain with a characteristic sequence for binding to catenins. Type I cadherins differ from type II cadherins by the presence of the HAV tripeptide motif in the most N-terminal cadherin repeat. Classic cadherins mediate cell-cell adhesion preferentially via homotypic interactions and form adherens juctions that have beta -catenin and p120 (ctn) at the cytoplasmic side of the junction. Homotypic cadherin interactions also transduce outside-in and inside-out cell signals.

Molecular Weight: 120 kDa

Gene ID: 12552

NCBI Accession: NP_033996

UniProt: P55288