Foxk1 antibody

Catalog No. ABIN7073970

The Rabbit Polyclonal anti-Foxk1 antibody has been validated for WB, IHC and IF. It is suitable to detect Foxk1 in samples from Human, Mouse and Rat.

Quick Overview for Foxk1 antibody (ABIN7073970)

Target: Foxk1 (Forkhead Box K1 (Foxk1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Foxk1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Foxk1 Antibody

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse FOXK1/MNF

Application Details

Application Notes: WB (H) 1:500-1:1000, IHC/IF (H,M,R) 1:1000-1:2000/1:650-1:1300

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Foxk1

Target: Foxk1 (Forkhead Box K1 (Foxk1))

Alternative Name: FOXK1/MNF

Background: The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. In skeletal muscles, undifferentiated myogenic stem cells (satellite cells) can mobilize to regenerate myofibers in response to injury. FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus.

Molecular Weight: 97 kDa

Gene ID: 17425

NCBI Accession: NP_951031

UniProt: P42128