UBA7 antibody (AA 401-500) (Biotin)

Catalog No. ABIN704503

This Rabbit Polyclonal antibody specifically detects UBA7 in IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for UBA7 antibody (AA 401-500) (Biotin) (ABIN704503)

Target: UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBA7 antibody is conjugated to Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-UBA7 Antibody (Biotin)

Binding Specificity: AA 401-500

Predicted Reactivity: Human,Mouse,Rat,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Ube1L

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for UBA7

Target: UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))

Alternative Name: Ube1L/UBE2

Background:

Synonyms: D8, UBA7, Ube 1L, UBE 2, UBE2, Ubiquitin activating enzyme 2, Ubiquitin activating enzyme E1 homolog, Ubiquitin Activating Enzyme E1 Like, Ubiquitin activating enzyme E1 related protein, UBA7_HUMAN.

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008].

Gene ID: 7318