SERCA2 ATPase antibody
Quick Overview for SERCA2 ATPase antibody (ABIN7075544)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Rat
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Purification
- Affinity purification
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Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse SERCA2 ATPase
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Application Notes
- WB (M,R) 1:1000-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- SERCA2 ATPase
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Background
- ATP dependent calcium pumps are responsible, in part, for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium (SERCA) ATPases. The SERCA1 gene is exclusively expressed in type II (fast) skeletal muscle. The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific form expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types.
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Molecular Weight
- 115 kDa
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Gene ID
- 11938
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NCBI Accession
- NP_001103610
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UniProt
- O55143
Target
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