Histone H4 antibody (AA 51-103)

Catalog No. ABIN704681

The Rabbit Polyclonal anti-Histone H4 antibody has been validated for ELISA and FACS. It is suitable to detect Histone H4 in samples from Human and Rat. There is 1 publication available.

Quick Overview for Histone H4 antibody (AA 51-103) (ABIN704681)

Target: Histone H4

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H4 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Product Details anti-Histone H4 Antibody

Binding Specificity: AA 51-103

Predicted Reactivity: Mouse,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Histone H4

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Histone H4 antibody (ABIN704681)

Qian, Zhang, Hu, Xu, Chen, Hu, Zhao, Liu: "Silver nanoparticle-induced hemoglobin decrease involves alteration of histone 3 methylation status." in: Biomaterials, Vol. 70, pp. 12-22, (2015) (PubMed).

Target Details for Histone H4

Target: Histone H4

Background:

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Subcellular location: Nucleus

Synonyms: H4/p, Histone H4, HIST1H4A, H4/A, H4FA

Gene ID: 121504

UniProt: P62805