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TTL antibody
TTL
Reactivity: Mouse, Rat
IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TTL Antibody
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Target
See all TTL Antibodies
TTL
(Tubulin tyrosine Ligase (TTL))
Reactivity
All reactivities for TTL antibodies
Mouse, Rat
Host
All hosts for TTL antibodies
Rabbit
Clonality
All clonalities for TTL antibodies
Polyclonal
Conjugate
All conjugates for TTL antibodies
This TTL antibody is un-conjugated
Application
All applications for TTL antibodies
Immunohistochemistry (IHC), Immunofluorescence (IF)
Cross-Reactivity
Rat
Purification
Affinity purification
Immunogen
Recombinant protein corresponding to Mouse TTL
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Alternatives
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Application Details
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Application Notes
IHC/IF (M,R) 1:2000-1:4000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Target Details for TTL
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Target
TTL
(Tubulin tyrosine Ligase (TTL))
Alternative Name
TTL (TTL Products )
Background
Tubulin-tyrosine ligase (TTL) is the enzyme responsible for the reversible addition of a tyrosine residue at the carboxyl end of alpha-tubulin. TTL forms stable complexes with tubulin and inhibit tubulin polymerization. TTL is frequently suppressed during tumor progression with resulting accumulation of detyrosinated alpha-tubulin in tumor cells. TTL suppression in human cancers is associated with increased tumor aggressiveness.
Gene ID
69737
NCBI Accession
NP_081468
UniProt
P38585
Pathways
Regulation of Cell Size
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