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TNFRSF6B antibody
TNFRSF6B
Reactivity: Human, Mouse, Rat
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TNFRSF6B Antibody
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Target
See all TNFRSF6B Antibodies
TNFRSF6B
(Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))
Reactivity
Human, Mouse, Rat
Host
All hosts for TNFRSF6B antibodies
Rabbit
Clonality
All clonalities for TNFRSF6B antibodies
Polyclonal
Conjugate
All conjugates for TNFRSF6B antibodies
This TNFRSF6B antibody is un-conjugated
Application
All applications for TNFRSF6B antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Cross-Reactivity
Mouse, Rat
Purification
Affinity purification
Immunogen
Recombinant protein corresponding to Human DcR3
Alternatives
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Application Details
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Application Notes
WB (H,M,R) 1:500-1:1000, IHC/IF (H,M,R) 1:700-1:1400
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Target Details for TNFRSF6B
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Target
TNFRSF6B
(Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))
Alternative Name
DcR3 (TNFRSF6B Products )
Synonyms
DCR3 antibody, DJ583P15.1.1 antibody, M68 antibody, M68E antibody, TR6 antibody, dcr3 antibody, m68 antibody, tr6 antibody, TNF receptor superfamily member 6b antibody, tumor necrosis factor receptor superfamily, member 11b antibody, regulator of telomere elongation helicase 1 antibody, TNF receptor superfamily member 6b L homeolog antibody, TNFRSF6B antibody, tnfrsf11b antibody, RTEL1 antibody, tnfrsf6b antibody, tnfrsf6b.L antibody
Background
Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively. Unlike DcR1and DcR2, DcR3 is a soluble rather than a membraneassociated molecule. DcR3 binds to FasL and LIGHT andinhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and coloncarcinomas and in some normal tissues.
Molecular Weight
33 kDa
Gene ID
8771
NCBI Accession
NP_003814
UniProt
O95407
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