TNFRSF6B antibody

Catalog No. ABIN7076071

This anti-TNFRSF6B antibody is a Rabbit Polyclonal antibody detecting TNFRSF6B in WB, IHC and IF. Suitable for Human, Mouse and Rat.

Quick Overview for TNFRSF6B antibody (ABIN7076071)

Target: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFRSF6B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TNFRSF6B Antibody

Cross-Reactivity: Mouse, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Human DcR3

Application Details

Application Notes: WB (H,M,R) 1:500-1:1000, IHC/IF (H,M,R) 1:700-1:1400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for TNFRSF6B

Target: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Alternative Name: DcR3

Background: Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively. Unlike DcR1and DcR2, DcR3 is a soluble rather than a membraneassociated molecule. DcR3 binds to FasL and LIGHT andinhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and coloncarcinomas and in some normal tissues.

Molecular Weight: 33 kDa

Gene ID: 8771

NCBI Accession: NP_003814

UniProt: O95407