CD3 antibody (FITC)

Catalog No. ABIN7077124

The Mouse Monoclonal anti-CD3 antibody has been validated for FACS. It is suitable to detect CD3 in samples from Human and Chimpanzee.

Quick Overview for CD3 antibody (FITC) (ABIN7077124)

Target: CD3

Reactivity: Human, Chimpanzee

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD3 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: SK7

Product Details anti-CD3 Antibody (FITC)

Purpose: CD3 FITC Antibody

Characteristics: The monoclonal SK7 clone recognizes antigen CD3ε epsilon, a 20KDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The CD3 complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor - CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. CD3ε is expressed on T lymphocytes, NK-T cells, and to a varying degree in developing thymocytes. CD3 plays central roles in TCR signaling, T lymphocyte activation, and antigen recognition.

Purification: Purified

Purity: >95 %

Immunogen: Human Thymocytes

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C, Conjugated antibodies should never be frozen.

Target Details for CD3

Target: CD3

Alternative Name: CD3

Gene ID: 916

NCBI Accession: NM_000733

UniProt: P07766

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway