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Cullin 2 antibody (CUL2) (HRP) Primary Antibody

CUL2 Reactivity: Human, Mouse, Rat IHC (p), WB Host: Rabbit Polyclonal HRP
Catalog No. ABIN705275
$442.20
Plus shipping costs $45.00
100 μL
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Delivery in 11 to 16 Business Days
  • Target
    Cullin 2 (CUL2)
    Reactivity
    Human, Mouse, Rat
    • 75
    • 59
    • 37
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    This Cullin 2 antibody is conjugated to HRP
    • 38
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    • 59
    • 41
    • 19
    • 16
    • 13
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Cullin 2
    Isotype
    IgG
  • Application Notes
    WB 1:100-1000
    IHC-P 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
    Preservative
    Gentamicin sulfate
    Precaution of Use
    This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Storage
    4 °C
    Storage Comment
    Store at 4°C
    Expiry Date
    12 months
  • Target
    Cullin 2 (CUL2)
    Alternative Name
    Cullin 2 (CUL2 Antibody Abstract)
    Synonyms
    cul2, Cullin-2, fj48a06, wu:fj48a06, cullin-2, LOC100221330, 1300003D18Rik, 4932411N15Rik, AI327301, mKIAA4106, ATCUL2, F22D16.2, F22D16_2, cullin 2, cullin 2, cullin-2, putative cullin-2 (cul-2), cullin 2 L homeolog, Cullin-2, cul2, CUL2, PTRG_05231, Smp_079740, LOC100550749, Cul2, cul2.L, cul-2
    Background

    Cullin 2 is a member of the family of human Cullin genes (CUL1, 2, 3, 4a, 4b and 5) homologous to the S. cerevisiae cdc53 gene. It is a component of E3 ubiquitin ligase complexes, including the inactive transcriptional elongation complex SIII, which mediates the ubiquitination of hypoxia-inducible factor (HIF). SIII is formed by three subunits: Elongin C, Elongin B and VHL. Cullin 2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.

    Synonyms: Cullin2, Cullin-2, CUL 2, MGC131970, CUL2_HUMAN.

    Gene ID
    8453
    Pathways
    M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome
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