TBL1Y antibody (AA 501-577) (Cy5.5)

Catalog No. ABIN705421

This Rabbit Polyclonal antibody specifically detects TBL1Y in WB, IF (cc) and IF (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TBL1Y antibody (AA 501-577) (Cy5.5) (ABIN705421)

Target: TBL1Y (Transducin (Beta)-Like 1, Y-Linked (TBL1Y))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBL1Y antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-TBL1Y Antibody (Cy5.5)

Binding Specificity: AA 501-577

Specificity: 100 % sequence similarity with TBL1Y

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TBL1X

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TBL1Y

Target: TBL1Y (Transducin (Beta)-Like 1, Y-Linked (TBL1Y))

Alternative Name: TBL1

Background:

Synonyms: TBL1, EBI, F box like/WD repeat protein TBL1X, SMAP 55, SMAP55, TBL 1, TBL1X, Transducin beta like 1, Transducin beta like 1 X linked, Transducin beta like 1 X linked, Transducin beta like 1X, Transducin beta like 1X protein, TBL1X_HUMAN, F-box-like/WD repeat-containing protein TBL1X, Full=Transducin beta-like protein 1X, Transducin-beta-like protein 1, X-linked..

Background: The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene. [provided by RefSeq].

Gene ID: 6907, 90665