PACAP antibody

Catalog No. ABIN7090726

The Mouse Monoclonal anti-PACAP antibody is suitable to detect PACAP in samples from Human. It has been validated for WB.

Quick Overview for PACAP antibody (ABIN7090726)

Target: PACAP (ADCYAP1) (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PACAP antibody is un-conjugated

Application: Western Blotting (WB)

Clone: G8R3

Product Details anti-PACAP Antibody

Predicted Reactivity: Human

Immunogen: Recombinant human ADCYAP1.

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PACAP

Target: PACAP (ADCYAP1) (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1))

Alternative Name: ADCYAP1

Background:

Synonyms: Adenylate Cyclase Activating Polypeptide 1 (Pituitary), Prepro-PACAP, PACAP, Pituitary Adenylate Cyclase Activating Polypeptide, PRP-48, PACAP27, PACAP38, ADCYAP1, PACA_HUMAN,

Background: Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells.

Gene ID: 116

UniProt: P18509

Pathways: Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Activity, cAMP Metabolic Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Regulation of G-Protein Coupled Receptor Protein Signaling