BMP6 antibody
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- Target See all BMP6 Antibodies
- BMP6 (Bone Morphogenetic Protein 6 (BMP6))
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This BMP6 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Cross-Reactivity
- Human, Rat
- Predicted Reactivity
- Mouse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human BMP6
- Clone
- D9F5
- Isotype
- IgG, kappa
- Top Product
- Discover our top product BMP6 Primary Antibody
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- Application Notes
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WB 1:300-5000
IF()
ICC 1:100-500 - Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- BMP6 (Bone Morphogenetic Protein 6 (BMP6))
- Alternative Name
- BMP6 (BMP6 Products)
- Background
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Synonyms: Bone Morphogenic Protein 6, Decapentaplegic vegetal related, DVR6, BMP 6, BMP-6, TGFB related vegetal related growth factor, Transforming growth factor beta, Vegetal related (TGFB related) cytokine, Vg related sequence, VGR, VGR1, BMP6_HUMAN.
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016]
- Gene ID
- 654
- UniProt
- P22004
- Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
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