CCR4 antibody (AA 171-220) (HRP)

Catalog No. ABIN7090978

The Rabbit Polyclonal anti-CCR4 antibody has been validated for ELISA, WB, IHC (p) and IHC (fro). It is suitable to detect CCR4 in samples from Human and Rat.

Quick Overview for CCR4 antibody (AA 171-220) (HRP) (ABIN7090978)

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR4 antibody is conjugated to HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CCR4 Antibody (HRP)

Binding Specificity: AA 171-220

Cross-Reactivity: Human, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCR4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Target Details for CCR4

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Alternative Name: CCR4

Background:

Synonyms: CC chemokine receptor 4, chemokine (C-C motif) receptor 4, CC-CKR-4, CCR-4, CD194, CHEMOKINE CC4 RECEPTOR, CHEMR1, ChemR13, CKR4, CMKBR4, HGCN:14099, K5-5, LESTR, MGC151418, MGC88293, nocturnin, Sdf1r, chemokine C C motif receptor 4, ChemR13, CCR4_HUMAN, C-C chemokine receptor type 4, K5-5, CD 194, CD-194.

Background: High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.

Gene ID: 1233

UniProt: P51679