G6PC2 antibody (AA 191-290) (Biotin)

Catalog No. ABIN7091160

This Rabbit Polyclonal antibody specifically detects G6PC2 in WB. It exhibits reactivity toward Mouse and Rat.

Quick Overview for G6PC2 antibody (AA 191-290) (Biotin) (ABIN7091160)

Target: G6PC2 (Glucose-6-Phosphatase, Catalytic, 2 (G6PC2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This G6PC2 antibody is conjugated to Biotin

Application: Western Blotting (WB)

Product Details anti-G6PC2 Antibody (Biotin)

Binding Specificity: AA 191-290

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase 2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for G6PC2

Target: G6PC2 (Glucose-6-Phosphatase, Catalytic, 2 (G6PC2))

Alternative Name: Glucose 6 phosphatase 2

Background:

Synonyms: G 6 Pase 2, G 6 Pase2, G6Pase 2, G6Pase2, G6PC 2, G6pc rs, G6pcrs, Glucose 6 phosphatase 2, Glucose 6 phosphatase, catalytic, 2, Glucose 6 phosphatase, catalytic, related, Glucose 6 phosphate catalytic 2, Islet specific G6CP related protein, Islet specific glucose 6 phosphatase, Islet specific glucose 6 phosphatase catalytic subunit related protein, G6PC2_HUMAN.

Background: IGRP (islet specific glucose 6 phosphatase catalytic subunit related protein), also known as G6PC2, belongs to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyses the hydrolysis of glucose-6-phosphate. This hydrolysis is the terminal step in gluconeogenic and glycogenolytic pathways, and allows the release of glucose into the bloodstream. IGRP is found in pancreatic islets and does not exhibit phosphohydrolase activity. However, it is a major target of cell-mediated autoimmunity in diabetes.

Gene ID: 57818

UniProt: Q9NQR9