KLRK1 antibody

Catalog No. ABIN7091315

This anti-KLRK1 antibody is a Rabbit Polyclonal antibody detecting KLRK1 in WB, ELISA, ICC, IHC (fro), IHC (p) and IF. Suitable for Mouse.

Quick Overview for KLRK1 antibody (ABIN7091315)

Target: KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLRK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-KLRK1 Antibody

Cross-Reactivity: Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse NKG2D

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF()
ICC 1:100-500

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for KLRK1

Target: KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))

Alternative Name: NKG2D

Background:

Synonyms: KLRK1, natural killer cell group 2D, NKG2-D isoform b, Klrk1, Nkrp2, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NK cell receptor D, Killer cell lectin-like receptor subfamily K, NK lectin-like receptor, CD314, CD 314, CD314 antigen, D12S2489E, Killer cell lectin like receptor subfamily K member 1, Killer cell lectin-like receptor subfamily K member 1, KLR, Klrk1, NKG2 D activating NK receptor, NKG2 D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2D_HUMAN, NKLLR, NKR P2, Nkrp2.

Background: Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.

Gene ID: 27007

UniProt: O54709

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process