TSG101 antibody

Catalog No. ABIN7091794

The Mouse Monoclonal anti-TSG101 antibody is suitable to detect TSG101 in samples from Human. It has been validated for WB.

Quick Overview for TSG101 antibody (ABIN7091794)

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TSG101 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: G6F4

Product Details anti-TSG101 Antibody

Predicted Reactivity: Human

Immunogen: Recombinant human TSG101.

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TSG101

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Alternative Name: TSG101

Background:

Synonyms: Tumor susceptibility gene 101 protein, ESCRT I complex subunit TSG101, ESCRT-I complex subunit TSG101, TSG 10, TSG 101, TSG10, Tumor susceptibility gene 10, Tumor susceptibility gene 101, Tumor susceptibility protein, Tumor susceptibility protein isoform 3, VPS 23, VPS23, TS101_HUMAN.

Background: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.

Gene ID: 7251

UniProt: Q99816