TSG101 antibody
Quick Overview for TSG101 antibody (ABIN7091794)
Target
See all TSG101 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Predicted Reactivity
- Human
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Immunogen
- Recombinant human TSG101.
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Application Notes
- WB 1:300-5000
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Restrictions
- For Research Use only
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Concentration
- 0.5 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Expiry Date
- 12 months
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- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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Alternative Name
- TSG101
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Background
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Synonyms: Tumor susceptibility gene 101 protein, ESCRT I complex subunit TSG101, ESCRT-I complex subunit TSG101, TSG 10, TSG 101, TSG10, Tumor susceptibility gene 10, Tumor susceptibility gene 101, Tumor susceptibility protein, Tumor susceptibility protein isoform 3, VPS 23, VPS23, TS101_HUMAN.
Background: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.
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Gene ID
- 7251
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UniProt
- Q99816
Target
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