TIM3 antibody (AA 22-202)

Catalog No. ABIN7092882

This Rabbit Monoclonal antibody specifically detects TIM3 in FACS and ELISA. It exhibits reactivity toward Human.

Quick Overview for TIM3 antibody (AA 22-202) (ABIN7092882)

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TIM3 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA

Clone: DM81

Product Details anti-TIM3 Antibody

Binding Specificity: AA 22-202

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogen: Recombinant human TIM3 (Ser22-Gly202) (ABIN6961103) produced by using human HEK293 cells

Isotype: IgG

Application Details

Application Notes: ELISA 1/5000-10000,Flow Cyt  1/100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for TIM3

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Alternative Name: TIM3

Target Type: Virus

Background: Synonyms:HAVCR2, TIM3, TIMD3, FLJ14428, KIM3
Description:The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Molecular Weight: 33.4kDa

Gene ID: 84868

UniProt: Q8TDQ0

Pathways: Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints