ACOT7 antibody

Catalog No. ABIN7111284

This anti-ACOT7 antibody is a Rabbit Polyclonal antibody detecting ACOT7 in WB, ELISA and IHC. Suitable for Human, Mouse and Rat. This Primary Antibody has been cited in 1 publication.

Quick Overview for ACOT7 antibody (ABIN7111284)

Target: ACOT7 (Acyl-CoA Thioesterase 7 (ACOT7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACOT7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ACOT7 Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: acyl-CoA thioesterase 7

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:5000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

References for anti-ACOT7 antibody (ABIN7111284)

Jakopovic, Horvatić, Baranasic, Car, Oršolić, Jakopovich, Sedić, Kraljević Pavelić: "Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic pathways." in: Frontiers in pharmacology, Vol. 15, pp. 1475102, (2024) (PubMed).

Target Details for ACOT7

Target: ACOT7 (Acyl-CoA Thioesterase 7 (ACOT7))

Alternative Name: ACOT7

Background: Synonyms:ACOT7, LACH1, LACH, acyl CoA thioesterase 7, ACH1 Background:Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A(CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May play an important physiological function in brain. May play a regulatory role by modulating the cellular levels of fatty acyl-CoA ligands for certain transcription factors as well as the substrates for fatty acid metabolizing enzymes, contributing to lipid homeostasis. Has broad specificity, active towards fatty acyl-CoAs with chain-lengths of C8-C18. Has a maximal activity toward palmitoyl-CoA.

Molecular Weight: 40 kDa

Gene ID: 11332

UniProt: O00154

Pathways: Monocarboxylic Acid Catabolic Process