ARRDC3 antibody

Catalog No. ABIN7111730

The Rabbit Polyclonal anti-ARRDC3 antibody has been validated for ELISA, WB and IF. It is suitable to detect ARRDC3 in samples from Human.

Quick Overview for ARRDC3 antibody (ABIN7111730)

Target: ARRDC3 (Arrestin Domain Containing 3 (ARRDC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARRDC3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ARRDC3 Antibody

Purpose: ARRDC3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: arrestin domain containing 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ARRDC3

Target: ARRDC3 (Arrestin Domain Containing 3 (ARRDC3))

Alternative Name: ARRDC3

Background:

Synonyms: Arrestin domain-containing protein 3|TBP-2-like inducible membrane protein (TLIMP)|ARRDC3|KIAA1376

Background: Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors(PubMed:20559325, PubMed:21982743, PubMed:23208550). Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation(PubMed:20559325, PubMed:23208550). May recruit NEDD4 to ADRB2(PubMed:20559325). Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes(PubMed:23208550).

Molecular Weight: 46 kDa

Gene ID: 57561

UniProt: Q96B67