BACE1 antibody (AA 150-457)

Catalog No. ABIN7111995

This anti-BACE1 antibody is a Rabbit Polyclonal antibody detecting BACE1 in WB, IHC, ELISA and IP. Suitable for Human, Mouse and Rat.

Quick Overview for BACE1 antibody (AA 150-457) (ABIN7111995)

Target: BACE1 (Beta-secretase 1 (BACE1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BACE1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Product Details anti-BACE1 Antibody

Binding Specificity: AA 150-457

Purpose: BACE1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 150-457aa

Immunogen: beta-site APP-cleaving enzyme 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:100-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for BACE1

Target: BACE1 (Beta-secretase 1 (BACE1))

Alternative Name: BACE1

Background:

Synonyms: Beta-secretase 1|Aspartyl protease 2 (ASP2, Asp 2)|Beta-site amyloid precursor protein cleaving enzyme 1 (Beta-site APP cleaving enzyme 1)|Memapsin-2|Membrane-associated aspartic protease 2|BACE1|BACE|KIAA1149

Background: Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

Molecular Weight: 70-75 kDa

Gene ID: 23621

UniProt: P56817