BACE1 antibody

Catalog No. ABIN7111995

This anti-BACE1 antibody is a Rabbit Polyclonal antibody detecting BACE1 in WB, IHC, ELISA and IP. Suitable for Human, Mouse and Rat.

Quick Overview for BACE1 antibody (ABIN7111995)

Target: BACE1 (Beta-secretase 1 (BACE1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BACE1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Product Details anti-BACE1 Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: beta-site APP-cleaving enzyme 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:100-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for BACE1

Target: BACE1 (Beta-secretase 1 (BACE1))

Alternative Name: BACE1

Background: Synonyms:BACE, KIAA1149 Background:Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

Molecular Weight: 70-75 kDa

Gene ID: 23621

UniProt: P56817