CRCP antibody

Catalog No. ABIN7112634

This anti-CRCP antibody is a Rabbit Polyclonal antibody detecting CRCP in ELISA, WB, IHC, IP and FACS. Suitable for Human, Mouse and Rat.

Quick Overview for CRCP antibody (ABIN7112634)

Target: CRCP (CGRP Receptor Component (CRCP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRCP antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS)

Product Details anti-CRCP Antibody

Purpose: CRCP antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: CGRP receptor component

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:4000, IP: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CRCP

Target: CRCP (CGRP Receptor Component (CRCP))

Alternative Name: CRCP

Background:

Synonyms: DNA-directed RNA polymerase III subunit RPC9 (RNA polymerase III subunit C9)|Calcitonin gene-related peptide-receptor component protein (CGRP-RCP, CGRP-receptor component protein, CGRPRCP, HsC17)|CRCP

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF-Kappa-B through the RIG-I pathway(By similarity).

Molecular Weight: 20 kDa

Gene ID: 27297

UniProt: O75575