CYP4F8
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Application Notes
IHC: 1:20-1:200
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target
CYP4F8
(Cytochrome P450, Family 4, Subfamily F, Polypeptide 8 (CYP4F8))
Alternative Name
CYP4F8
Background
Synonyms: Background:Hydroxylates arachidonic acid(20:4n-6) to(18R)-hydroxyarachidonate. Shows little activity against prostaglandin(PG) D2, PGE1, PGE2, PGF2alpha, and leukotriene B4. Catalyzes omega-2 and omega-3-hydroxylation of PGH1 and PGH2. Catalyzes epoxidation of 4,7,10,13,16,19-(Z)-docosahexaenoic acid(22:6n-3) and 7,10,13,16,19-(Z)-docosapentaenoic acid(22:5n-3) and omega-3-hydroxylation of 4,7,10,13,16-(Z)-docosapentaenoic acid(22:5n-6). Catalyzes hydroxylation of PGI2 and carbaprostacyclin.