DBF4 antibody
Quick Overview for DBF4 antibody (ABIN7113319)
Target
See all DBF4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- DBF4 antibody
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Purification
- Immunogen affinity purified
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Purity
- ≥95 % as determined by SDS-PAGE
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Immunogen
- DBF4 homolog
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Isotype
- IgG
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Application Notes
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Storage Comment
- -20°C for 12 months
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Expiry Date
- 12 months
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- DBF4 (DBF4 Homolog (DBF4))
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Alternative Name
- DBF4
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Background
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Synonyms: Protein DBF4 homolog A|Activator of S phase kinase|Chiffon homolog A|DBF4-type zinc finger-containing protein 1|DBF4|ASK|DBF4A|ZDBF1
Background: Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
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Molecular Weight
- 70-80 kDa
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Gene ID
- 10926
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UniProt
- Q9UBU7
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Pathways
- Mitotic G1-G1/S Phases, DNA Replication
Target
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