ELK4 antibody

Catalog No. ABIN7113769

This Rabbit Polyclonal antibody specifically detects ELK4 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ELK4 antibody (ABIN7113769)

Target: ELK4 (ELK4, ETS-Domain Protein (SRF Accessory Protein 1) (ELK4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ELK4 Antibody

Purpose: ELK4 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ELK4, ETS-domain protein(SRF accessory protein 1)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ELK4

Target: ELK4 (ELK4, ETS-Domain Protein (SRF Accessory Protein 1) (ELK4))

Alternative Name: ELK4

Background:

Synonyms: ETS domain-containing protein Elk-4|Serum response factor accessory protein 1 (SAP-1, SRF accessory protein 1)|ELK4|SAP1

Background: Involved in both transcriptional activation and repression. Interaction with SIRT7 leads to recruitment and stabilization of SIRT7 at promoters, followed by deacetylation of histone H3 at 'Lys-18'(H3K18Ac) and subsequent transcription repression. Forms a ternary complex with the serum response factor(SRF). Requires DNA-bound SRF for ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously.

Molecular Weight: 47 kDa

Gene ID: 2005

UniProt: P28324