FGD5 antibody

Catalog No. ABIN7114385

The Rabbit Polyclonal anti-FGD5 antibody has been validated for ELISA, WB, IHC and IF. It is suitable to detect FGD5 in samples from Human, Mouse and Rat.

Quick Overview for FGD5 antibody (ABIN7114385)

Target: FGD5 (FYVE, RhoGEF and PH Domain Containing 5 (FGD5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGD5 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FGD5 Antibody

Purpose: FGD5 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: FYVE, RhoGEF and PH domain containing 5

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for FGD5

Target: FGD5 (FYVE, RhoGEF and PH Domain Containing 5 (FGD5))

Alternative Name: FGD5

Background:

Synonyms: FYVE, RhoGEF and PH domain-containing protein 5|Zinc finger FYVE domain-containing protein 23|FGD5|ZFYVE23

Background: Activates CDC42, a member of the Ras-like family of Rho-and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.

Molecular Weight: 160 kDa

Gene ID: 152273

UniProt: Q6ZNL6