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HNRNPC antibody
HNRNPC
Reactivity: Human, Rat, Mouse
WB, ELISA, IHC, IF, FACS
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-HNRNPC Antibody
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Target
See all HNRNPC Antibodies
HNRNPC
(Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
Reactivity
All reactivities for HNRNPC antibodies
Human, Rat, Mouse
Host
All hosts for HNRNPC antibodies
Rabbit
Clonality
All clonalities for HNRNPC antibodies
Polyclonal
Conjugate
All conjugates for HNRNPC antibodies
This HNRNPC antibody is un-conjugated
Application
All applications for HNRNPC antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
heterogeneous nuclear ribonucleoprotein C(C1/C2)
Isotype
IgG
Top Product
Discover our top product HNRNPC Primary Antibody
Alternatives
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anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) antibody
HNRNPC
Reactivity: Human, Rabbit, Cow, Dog, Pig, Monkey, Horse, Goat, Guinea Pig, Hamster
WB, IHC, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for HNRNPC
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Target
HNRNPC
(Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
Alternative Name
HNRNPC (HNRNPC Products )
Synonyms
C1 antibody, C2 antibody, HNRNP antibody, HNRPC antibody, SNRPC antibody, MGC53243 antibody, HNRNPC antibody, bZ1G18.4 antibody, fb57h12 antibody, fi16b11 antibody, wu:fb57h12 antibody, wu:fi16b11 antibody, zgc:55701 antibody, AL022939 antibody, D14Wsu171e antibody, Hnrpc antibody, Hnrpc1 antibody, Hnrpc2 antibody, hnRNPC1 antibody, hnRNPC2 antibody, hnrnp-C antibody, hnRNP C antibody, hnrnp antibody, hnrpc antibody, snrpc antibody, heterogeneous nuclear ribonucleoprotein C (C1/C2) antibody, heterogeneous nuclear ribonucleoprotein C (C1/C2) S homeolog antibody, heterogeneous nuclear ribonucleoprotein C antibody, heterogeneous nuclear ribonucleoprotein C (C1/C2) L homeolog antibody, HNRNPC antibody, hnrnpc.S antibody, hnrnpc antibody, Hnrnpc antibody, hnrnpc.L antibody
Background
Synonyms:HNRPC Background:Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles(PubMed:8264621). Specifically recognizes and binds N6-methyladenosine(m6A)-containing RNAs, a modification present at internal sites of mRNAs that affects mRNA splicing, processing and stability. M6A alters the local structure in mRNAs and long non-coding RNAs(lncRNAs) via a mechanism named 'm(6)A-switch' to facilitate binding of HNRNPC, leading to regulation of mRNA splicing(PubMed:25719671). Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules(PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621).
Molecular Weight
32 kDa
Gene ID
3183
UniProt
P07910
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