H2AC18 (AA 1-130) antibody
Quick Overview for H2AC18 (AA 1-130) antibody (ABIN7115039)
Target
Reactivity
Host
Clonality
Application
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Binding Specificity
- AA 1-130
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Purpose
- H2AC18 antibody
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Purification
- Immunogen affinity purified
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Purity
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 1-130aa
Immunogen: histone cluster 2, H2aa4
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Isotype
- IgG
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Application Notes
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Storage Comment
- -20°C for 12 months
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Expiry Date
- 12 months
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- H2AC18
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Background
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Synonyms: Histone H2A type 2-A|H2A-clustered histone 18|H2A-clustered histone 19|Histone H2A.2|Histone H2A/o|H2AC18|H2AFO|HIST2H2AA|HIST2H2AA3
Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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Molecular Weight
- 14 kDa
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Gene ID
- 8337
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UniProt
- Q6FI13
Target
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