HORMAD1 antibody

Catalog No. ABIN7115109

This anti-HORMAD1 antibody is a Rabbit Polyclonal antibody detecting HORMAD1 in ELISA and WB. Suitable for Human, Mouse and Rat.

Quick Overview for HORMAD1 antibody (ABIN7115109)

Target: HORMAD1 (HORMA Domain Containing 1 (HORMAD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HORMAD1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-HORMAD1 Antibody

Purpose: HORMAD1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: HORMA domain containing 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for HORMAD1

Target: HORMAD1 (HORMA Domain Containing 1 (HORMAD1))

Alternative Name: HORMAD1

Background:

Synonyms: HORMA domain-containing protein 1|Cancer/testis antigen 46 (CT46)|Newborn ovary HORMA protein|HORMAD1|NOHMA

Background: Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks(DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin(MSUC) and meiotic prophase quality control in both sexes(By similarity).

Molecular Weight: 45 kDa

Gene ID: 84072

UniProt: Q86X24

Pathways: M Phase