HIVEP1 antibody

Catalog No. ABIN7115120

The Rabbit Polyclonal anti-HIVEP1 antibody has been validated for ELISA and IHC. It is suitable to detect HIVEP1 in samples from Human.

Quick Overview for HIVEP1 antibody (ABIN7115120)

Target: HIVEP1 (Human Immunodeficiency Virus Type I Enhancer Binding Protein 1 (HIVEP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIVEP1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-HIVEP1 Antibody

Purpose: HIVEP1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: human immunodeficiency virus type I enhancer binding protein 1

Isotype: IgG

Application Details

Application Notes: IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for HIVEP1

Target: HIVEP1 (Human Immunodeficiency Virus Type I Enhancer Binding Protein 1 (HIVEP1))

Alternative Name: HIVEP1

Background:

Synonyms: Zinc finger protein 40|Cirhin interaction protein (CIRIP)|Gate keeper of apoptosis-activating protein (GAAP)|Human immunodeficiency virus type I enhancer-binding protein 1 (HIV-EP1)|Major histocompatibility complex-binding protein 1 (MBP-1)|Positive regulatory domain II-binding factor 1 (PRDII-BF1)|HIVEP1|ZNF40

Background: This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV-1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HIV-1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS(IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HIV-1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis.

Gene ID: 3096

UniProt: P15822