IGFBP3 antibody
Quick Overview for IGFBP3 antibody (ABIN7115295)
Target
See all IGFBP3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Purpose
- IGFBP3 antibody
-
Purification
- Immunogen affinity purified
-
Purity
- ≥95 % as determined by SDS-PAGE
-
Immunogen
- insulin-like growth factor binding protein 3
-
Isotype
- IgG
-
-
-
-
Application Notes
- WB: 1:200-1:500, IHC: 1:20-1:200, IF: 1:10-1:100
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- Avoid repeated freeze / thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- -20°C for 12 months
-
Expiry Date
- 12 months
-
-
- IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
-
Alternative Name
- IGFBP3
-
Background
-
Synonyms: Insulin-like growth factor-binding protein 3 (IBP-3, IGF-binding protein 3, IGFBP-3)|IGFBP3|IBP3
Background: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.
-
Molecular Weight
- 32 kDa
-
Gene ID
- 3486
-
UniProt
- P17936
-
Pathways
- Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding
Target
-