INTU antibody

Catalog No. ABIN7115501

The Rabbit Polyclonal anti-INTU antibody is suitable to detect INTU in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for INTU antibody (ABIN7115501)

Target: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTU antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-INTU Antibody

Purpose: INTU antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: inturned planar cell polarity effector homolog(Drosophila)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for INTU

Target: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Alternative Name: INTU

Background:

Synonyms: Protein inturned|Inturned planar cell polarity effector homolog|PDZ domain-containing protein 6|INTU|KIAA1284|PDZD6|PDZK6

Background: Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling(By similarity).

Molecular Weight: 80 kDa

Gene ID: 27152

UniProt: Q9ULD6