KIAA0586 antibody

Catalog No. ABIN7115666

The Rabbit Polyclonal anti-KIAA0586 antibody has been validated for ELISA and IHC. It is suitable to detect KIAA0586 in samples from Human and Mouse.

Quick Overview for KIAA0586 antibody (ABIN7115666)

Target: KIAA0586

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIAA0586 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-KIAA0586 Antibody

Purpose: Talpid3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: KIAA0586

Isotype: IgG

Application Details

Application Notes: IHC: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for KIAA0586

Target: KIAA0586

Alternative Name: Talpid3

Background:

Synonyms: Protein TALPID3|Talpid3

Background: Required for ciliogenesis and sonic hedgehog/SHH signaling(PubMed:21750036). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation(By similarity). Involved in regulation of cell intracellular organization(PubMed:26386247). Involved in regulation of cell polarity(By similarity). Required for asymmetrical localization of CEP120 to daughter centrioles(PubMed:25251415).

Gene ID: 76967

UniProt: E9PV87